Analytical Data
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Gene name
FOXE1
- Application
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Alternative Names
FKHL15; FOXE2; HFKH4; HFKL5; TITF2; TTF2; Thyroid Transcription Tactor 2; Forkhead-related protein FKHL15; HNF-3/fork head-like protein 5; Thyroid transcription factor 2
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8R2I0
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Expression Region
Asn127~Met371
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Molecular Weight
25kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXE1, a forkhead box transcription factor, plays a crucial role in the development and function of multiple organs, including the thyroid gland and the pituitary gland. Mutations or dysregulation of FOXE1 have been linked to various thyroid diseases, such as congenital hypothyroidism and autoimmune thyroiditis. Due to its significant biological implications, FOXE1 has attracted considerable attention in the field of molecular biology and genetics. The study of FOXE1 recombinant proteins facilitates a better understanding of its functional mechanics and interaction pathways, providing insights into its role in pathology. Researchers have utilized techniques such as recombinant DNA technology to produce FOXE1 proteins for in vitro assays, allowing them to investigate the protein's DNA-binding properties, transcriptional regulation, and its influence on cellular signaling pathways. By analyzing FOXE1 in controlled experimental settings, scientists aim to decipher its contribution to thyroid oncogenesis and other endocrine disorders, thus paving the way for potential therapeutic interventions. Overall, FOXE1 recombinant protein research is critical for elucidating the molecular underpinnings of thyroid-related conditions and may lead to novel strategies for diagnosis and treatment in clinical practice.
