Analytical Data
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基因名
FOXE1
- Application
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别名
FKHL15; FOXE2; HFKH4; HFKL5; TITF2; TTF2; Thyroid Transcription Tactor 2; Forkhead-related protein FKHL15; HNF-3/fork head-like protein 5; Thyroid transcription factor 2
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8R2I0
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表达区间
Asn127~Met371
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分子量
25kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOXE1, a forkhead box transcription factor, plays a crucial role in the development and function of multiple organs, including the thyroid gland and the pituitary gland. Mutations or dysregulation of FOXE1 have been linked to various thyroid diseases, such as congenital hypothyroidism and autoimmune thyroiditis. Due to its significant biological implications, FOXE1 has attracted considerable attention in the field of molecular biology and genetics. The study of FOXE1 recombinant proteins facilitates a better understanding of its functional mechanics and interaction pathways, providing insights into its role in pathology. Researchers have utilized techniques such as recombinant DNA technology to produce FOXE1 proteins for in vitro assays, allowing them to investigate the protein's DNA-binding properties, transcriptional regulation, and its influence on cellular signaling pathways. By analyzing FOXE1 in controlled experimental settings, scientists aim to decipher its contribution to thyroid oncogenesis and other endocrine disorders, thus paving the way for potential therapeutic interventions. Overall, FOXE1 recombinant protein research is critical for elucidating the molecular underpinnings of thyroid-related conditions and may lead to novel strategies for diagnosis and treatment in clinical practice.
