Analytical Data
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Gene name
AP2s1
- Application
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Alternative Names
AP17; AP17-DELTA; CLAPS2; Clathrin assembly protein 2 sigma small chain; HA2 17 kDa subunit; Plasma membrane adaptor AP-2 17 kDa protein
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53680
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Expression Region
Met1~Glu142
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Molecular Weight
18kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AP2s1, a member of the AP2 (Adaptor Protein 2) family, plays a critical role in various cellular processes, including endocytosis, vesicle trafficking, and signal transduction. This family of proteins is characterized by their ability to recognize and bind to specific sequences in membrane proteins, facilitating their sorting and transport within the cell. Recent studies have suggested that AP2s1 may be involved in the regulation of key cellular pathways, including those related to cancer progression, immune response, and neuronal functions. The study of AP2s1 recombinant proteins has gained traction due to their potential applications in understanding the molecular mechanisms underlying these processes. By producing AP2s1 in a recombinant form, researchers can investigate its structure, functions, and interactions with other cellular components, paving the way for the development of targeted therapies. Moreover, as an essential player in cellular signaling, AP2s1 could serve as a biomarker for certain diseases, further highlighting the importance of advancing research in this area. Understanding the dynamics of AP2s1 could not only elucidate its role in normal physiological conditions but also provide insights into its implications in pathological states, thereby contributing to the broader knowledge of cell biology and potential therapeutic interventions.
