Cat: IPD-X39084

Recombinant Mouse NXPH4 Protein,His

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Analytical Data

  • Gene name

    NXPH4

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NPH4

  • Species

    Mouse

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    G3X9N5

  • Expression Region

    His116~Gly304

  • Molecular Weight

    24&22kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NXPH4, or Neurexophilin 4, is a protein that plays a significant role in the nervous system by modulating neurotransmitter release and synaptic function. Understanding NXPH4 is vital because it is implicated in various neurobiological processes, including neural development, synaptic plasticity, and potentially in the pathology of neurodegenerative diseases. Recent studies have highlighted its association with synaptic transmission and interactions with neuronal receptors, suggesting that it could be a key player in maintaining synaptic integrity and function. Given the increasing prevalence of neurological disorders globally, the exploration of NXPH4 and its functional mechanisms has garnered attention in the scientific community. Researchers are focusing on the recombinant expression of NXPH4 to investigate its structure-function relationship and to explore its potential therapeutic applications. By producing NXPH4 as a recombinant protein, scientists can study its interactions at the cellular level, enabling a deeper understanding of its role in synaptic dynamics and its potential as a target for drug development aimed at treating synaptic dysfunctions in various neurological disorders. This research is crucial for developing strategies to mitigate the impact of diseases such as Alzheimer's and other neurodegenerative conditions, making NXPH4 a significant focus of contemporary neuroscience research.

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