Analytical Data
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Gene name
MID2
- Application
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Alternative Names
MID1; FXY2; RNF60; TRIM1; Midline-2; RING finger protein 60; Tripartite motif-containing protein 1; Probable E3 ubiquitin-protein ligase MID2; Midline defect 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UJV3
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Expression Region
Ser7~Glu258
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MID2, a member of the MID (Mitochondrial Inner Membrane Domain) protein family, has garnered significant attention in recent years due to its potential role in mitochondrial function and cellular metabolism. Mitochondria are crucial organelles involved in energy production, and their dysfunction is linked to various diseases, including neurodegenerative disorders and metabolic syndromes. MID2 has been implicated in the regulation of mitochondrial dynamics and potential interactions with other key proteins that govern organelle integrity and function. Research has indicated that MID2 may be involved in mitochondrial biogenesis and fission processes, highlighting its importance in maintaining cellular energy homeostasis. Additionally, the study of MID2-induced protein rearrangements offers insights into pathogen-host interactions, particularly its role in the immune response and stress-related pathways. Understanding the structural and functional dynamics of MID2 and its restructured forms could reveal novel therapeutic targets for diseases associated with mitochondrial dysfunction, positioning MID2 as a key player in cellular health and disease management. As research expands, the exploration of MID2's precise biological functions and mechanisms will contribute to a more comprehensive understanding of mitochondrial pathology and the development of targeted interventions.
