Analytical Data
-
基因名
FMO1
- Application
-
别名
Dimethylaniline oxidase 1; Fetal hepatic flavin-containing monooxygenase 1
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q01740
-
表达区间
Ala2~Leu271
-
分子量
34kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FMO1 (Flavin-containing Monooxygenase 1) is a critical enzyme in the family of flavin-dependent monooxygenases, involved in the metabolism of various endogenous and exogenous substrates, including drugs and xenobiotics. The study of FMO1 has gained significant attention due to its role in drug metabolism, detoxification processes, and individual variability in drug responses, which can lead to adverse drug reactions. Notably, FMO1 is expressed in various tissues, including the liver, and its activity can be influenced by genetic polymorphisms, disease states, and environmental factors. The recombinant production of FMO1 has become essential for elucidating its enzymatic mechanisms and substrate specificity, facilitating high-throughput screening in drug discovery. Furthermore, understanding the structural and functional properties of FMO1 is crucial for designing better therapeutic agents and predicting drug interactions. Recent advances in recombinant DNA technology and protein purification methods have enabled researchers to produce large quantities of active FMO1, fostering studies that explore its role in metabolism and the potential implications for personalized medicine. Overall, FMO1 recombinant protein research provides insights into the complexities of human metabolism and the impact of genetic diversity on pharmacotherapy.












