Analytical Data
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基因名
DNM3
- Application
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别名
Dyna III; Dynamin, testicular; T-dynamin
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UQ16
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表达区间
Met1~Thr323
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DNM3 (Dynamin 3) is a member of the dynamin family of GTPase enzymes, which are known to play crucial roles in membrane dynamics, vesicle trafficking, and endocytosis. Research into DNM3 is particularly significant as it contributes to our understanding of various physiological processes, including synaptic function and neuronal signaling. Studies have shown that DNM3 is selectively expressed in the brain, implicating it in neurodevelopmental and neurodegenerative disorders. Its unique function compared to other dynamins has sparked interest in elucidating its molecular mechanisms. Additionally, mutations in DNM3 have been linked to several neurological conditions, highlighting its potential as a therapeutic target. The recombinant expression of DNM3 protein allows for in-depth structural and functional analyses, enabling researchers to investigate its interactions with other proteins and its role in cellular pathways. Understanding DNM3 through recombinant technology will not only advance basic neuroscience knowledge but also provide insights into therapeutic strategies for related diseases.
