Analytical Data
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Gene name
PLCL2
- Application
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Alternative Names
PLCE2; Phospholipase C,Epsilon 2; Inactive phospholipase C-like protein 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UPR0
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Expression Region
Phe829~Glu1127
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Molecular Weight
37kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLCL2 (phospholipase C-like 2) is a member of the phospholipase C (PLC) family, which is known for its role in cellular signaling pathways that regulate various physiological processes, including cell growth, differentiation, and apoptosis. Unlike traditional PLCs that hydrolyze phosphatidylinositol bisphosphate (PIP2) to generate inositol trisphosphate (IP3) and diacylglycerol (DAG), PLCL2 possesses a unique mechanism and substrate specificity. Research indicates that PLCL2 is involved in immune response regulation and has implications in diseases, such as cancers and autoimmune disorders. Moreover, PLCL2 expression is regulated by various stimuli, suggesting its potential role in adaptive cellular responses. The recombinant expression of PLCL2 protein allows for detailed biochemical studies to elucidate its functional characteristics and interactions with other signaling molecules. Understanding PLCL2’s structure-function relationship and its involvement in signaling pathways can provide insights into therapeutic targets and biomarker development for diseases associated with dysregulated signaling. Therefore, the study of recombinant PLCL2 is crucial for uncovering its biological significance and potential clinical applications.
