Analytical Data
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Gene name
PTPRQ
- Application
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Alternative Names
PTPR-Q; Phosphatidylinositol phosphatase PTPRQ
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UMZ3
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Expression Region
Glu36~Thr294
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Molecular Weight
32kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPRQ (Protein Tyrosine Phosphatase Receptor Type Q) is a member of the receptor-type protein tyrosine phosphatase family, primarily involved in cellular signaling processes, neuronal development, and synaptic function. Research has indicated that PTPRQ plays a crucial role in various biological mechanisms, including cell proliferation, differentiation, and adhesion. Its expression is notably enriched in the cochlea, suggesting a vital function in hearing and vestibular systems, where mutations in PTPRQ are linked to hearing loss and other auditory disorders. The structural complexity of the PTPRQ protein, characterized by multiple extracellular domains, presents intriguing avenues for scientific inquiry, especially how its signaling pathways can influence neurodevelopmental processes. Given its importance in both normal physiology and pathophysiology, the recombinant expression of PTPRQ has become a focal point for investigations aimed at understanding its mechanistic roles in health and disease. Studies involving the recombinant protein are directed toward elucidating its functional characteristics, potential interactions with other proteins, and therapeutic implications, particularly in the context of auditory system disorders. As researchers delve deeper into the functional dynamics of PTPRQ, the potential for developing targeted therapies and innovative treatment strategies for related conditions continues to emerge, marking it as a significant subject within molecular and developmental biology.
