Analytical Data
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Gene name
SLC8A1
- Application
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Alternative Names
Na(+)/Ca(2+)-exchange protein 1 Solute carrier family 8 member 1
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Species
Human
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Source
Yeast
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P32418
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Expression Region
396-627aa
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Molecular Weight
27.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC8A1, also known as the sodium/calcium exchanger 1 (NCX1), is a crucial membrane protein that plays a significant role in cellular calcium homeostasis by facilitating the exchange of sodium and calcium ions across the plasma membrane. Its function is vital in various physiological processes, including cardiac and neuronal excitability, muscle contraction, and intracellular signaling pathways. Dysregulation of SLC8A1 has been implicated in several pathological conditions, such as heart disease, neurological disorders, and hypertension. The study of SLC8A1 recombinant protein has become increasingly important for understanding its molecular mechanisms and potential therapeutic targets. By expressing and purifying SLC8A1 in various heterologous systems, researchers aim to elucidate its structural features, ion binding properties, and transport kinetics. This research has significant implications for the development of drugs that can modulate SLC8A1 activity, offering potential treatment strategies for diseases associated with calcium dysregulation. Overall, the investigation of SLC8A1 recombinant protein not only enhances our fundamental knowledge of ion transport mechanisms but also paves the way for innovative approaches in drug discovery and development.
