Analytical Data
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Gene name
PTPN7
- Application
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Alternative Names
BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI; Hematopoietic protein-tyrosine phosphatase; Protein-tyrosine phosphatase LC-PTP
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P35236
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Expression Region
Pro52~Glu314
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Molecular Weight
32kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPN7, also known as Protein Tyrosine Phosphatase Non-Receptor Type 7, is an essential member of the protein tyrosine phosphatase family, which plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and immune responses. Dysregulation of PTPN7 has been implicated in several diseases, including autoimmune disorders and cancers, highlighting its significance in both health and disease. Recent studies have focused on the functional characterization of PTPN7 through the production of recombinant proteins, allowing researchers to delve deeper into its enzymatic mechanisms and interaction networks. By expressing and purifying PTPN7 in model systems, scientists are able to investigate its substrate specificity and regulatory pathways, offering insights into how PTPN7 modulates signaling cascades that influence cellular behavior. The study of PTPN7 as a recombinant protein not only aids in elucidating its biological roles but also presents potential therapeutic avenues for targeting PTPN7 in disease management. As the understanding of PTPN7's functions continues to expand, it may serve as a valuable biomarker or therapeutic target, paving the way for innovative strategies in treating related pathological conditions.
