Analytical Data
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基因名
Ren2
- Application
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别名
ChemerinRAR-responsive protein TIG2Tazarotene-induced gene 2 protein
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种属
Mouse
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P00796
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表达区间
64-351aa
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Ren2, a recombinant protein derived from the Renin-angiotensin system, plays a crucial role in regulating blood pressure, electrolyte balance, and overall cardiovascular health. It is primarily produced in the kidneys, where it catalyzes the conversion of angiotensinogen to angiotensin I, subsequently leading to the formation of angiotensin II, a potent vasoconstrictor. Research on Ren2 has gained attention due to its potential implications in hypertension and heart disease. As hypertension remains a leading health concern globally, understanding the molecular mechanisms and pathways involving Ren2 is essential for developing targeted therapies. Recombinant versions of Ren2 are utilized in experimental settings to elucidate its biological functions, investigate its interactions with various receptors, and explore its effects in vivo. Furthermore, studies have shown that modulation of Ren2 activity may offer new avenues for treating conditions like diabetic nephropathy, heart failure, and other cardiovascular disorders. Advances in genetic engineering and protein expression systems have facilitated the production of high-purity Ren2, enabling detailed biochemical and pharmacological studies. By unraveling the complexities of Ren2 and its role in cardiovascular physiology, researchers aim to contribute to innovative therapeutic strategies that address the pressing challenges of cardiovascular diseases.












