Cat: IPD-X38633

Recombinant Human, Mouse, Rat SNAP25 Protein,His

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Analytical Data

  • 基因名

    SNAP25

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RIC4; SEC9; SNAP; SUP; Super protein; Resistance To Inhibitors Of Cholinesterase 4 Homolog

  • 种属

    Human, Mouse, Rat

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    -

  • 表达区间

    Met1~Gly206

  • 分子量

    27kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SNAP25 (Synaptosomal-Associated Protein of 25 kDa) is a crucial protein involved in synaptic transmission and plays a significant role in the exocytosis process at the neuromuscular junction and central nervous system synapses. It is a member of the SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptor) protein family, which facilitates the fusion of synaptic vesicles with presynaptic membranes, enabling the release of neurotransmitters. Dysregulation or mutations in SNAP25 have been linked to several neuropsychiatric and neurological disorders, including schizophrenia, epilepsy, and attention deficit hyperactivity disorder (ADHD). As research continues to explore the molecular mechanisms underlying synaptic communication, recombinant SNAP25 proteins have become essential tools for studying protein interactions and function in vitro. Scientists utilize recombinant SNAP25 to investigate its role in neurotransmitter release, study binding interactions with other SNARE proteins, and examine its involvement in disease models. These studies enhance our understanding of synaptic dynamics and could further lead to the development of therapeutic strategies that target SNAP25-related pathways to treat neurological disorders. Overall, the study of recombinant SNAP25 proteins is integral to elucidating the complex processes of neurobiology and could pave the way for novel interventions in the treatment of synaptic dysfunctions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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