Analytical Data
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基因名
gABBR1
- Application
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别名
GABAB(1e); GABABR1; GABA-BR1; GABBR1-3; GPRC3A; HGB1a; Gamma-aminobutyric acid type B receptor subunit 1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBS5
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表达区间
Val199~Gly570
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分子量
44kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
gABBR1, a member of the G protein-coupled receptor (GPCR) family, has garnered significant interest in recent years due to its potential role in various physiological processes and disease states. GPCRs are crucial for mediating cellular responses to a plethora of extracellular signals, making them key targets in drug discovery. gABBR1, in particular, has been implicated in modulating neurotransmitter release and influencing neuronal signaling pathways, which may contribute to neuropsychiatric disorders. Understanding the structure and function of gABBR1 is essential for elucidating its mechanisms of action and therapeutic potential. Recent advancements in recombinant protein technology have enabled the production of gABBR1 in a more efficient manner, allowing researchers to study its ligand-binding properties and downstream signaling pathways in detail. These studies aim to uncover the functional dynamics of gABBR1 and its interactions with other cellular components, providing critical insights that could lead to novel therapeutic strategies for conditions characterized by GPCR dysregulation, such as depression and anxiety disorders. By generating and characterizing gABBR1 recombinant proteins, researchers can pave the way for the development of specific inhibitors or modulators that could improve treatment outcomes for patients suffering from related ailments.
