Analytical Data
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Gene name
COMMD4
- Application
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Alternative Names
COMD4_HUMAN; COMM domain containing 4; COMM domain-containing protein 4; COMMD4
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H0A8
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Expression Region
1-195aa
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Molecular Weight
48.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
COMMD4, a member of the Communicating Motif Domain (COMMD) family, has garnered significant attention due to its involvement in critical cellular processes such as copper homeostasis and the regulation of NF-kB signaling. Research indicates that COMMD4 plays a crucial role in the cellular response to stress, particularly through its action as a chaperone protein that facilitates the degradation of specific substrates via the ubiquitin-proteasome pathway. Given its potential impact on various biological functions, including inflammation and cancer progression, the study of COMMD4 recombinant protein has become essential for understanding its structural and functional properties. Investigating COMMD4 at a molecular level allows scientists to elucidate its interactions with other proteins and its regulatory mechanisms, paving the way for its potential therapeutic applications. Furthermore, recombinant COMMD4 protein production enables the exploration of its activity in vitro and in vivo, facilitating the development of targeted strategies to manipulate its functions in pathological conditions. Overall, the ongoing research into COMMD4 recombinant protein is expected to yield valuable insights into its contributions to cellular homeostasis and disease, highlighting its importance in biomedical research.
