Analytical Data
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基因名
SLC20A3
- Application
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别名
Citrate transport protein ;CTPSolute carrier family 25 member 1Tricarboxylate carrier protein
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P53007
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表达区间
47-87aa
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分子量
31.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC20A3, a member of the SLC20 gene family, encodes a sodium-dependent phosphate transporter predominantly expressed in various tissues, particularly in the kidney and bone. This transporter plays a critical role in phosphate homeostasis, which is essential for numerous biological processes, including bone mineralization, cellular signaling, and energy metabolism. Dysregulation of SLC20A3 has been linked to several pathological conditions, such as hypophosphatemic rickets and cardiovascular diseases, highlighting its importance in maintaining phosphate levels within normal ranges. Given its significant physiological roles and implications in diseases, research into the recombinant protein of SLC20A3 facilitates a better understanding of its structure, function, and biochemical properties. By producing and analyzing the SLC20A3 recombinant protein, scientists can explore its transport mechanisms, interaction with various ligands, and regulation by intracellular signaling pathways. Furthermore, such studies can lead to the identification of pharmacological targets for therapeutic interventions aiming to correct phosphate imbalances in related diseases. The recombinant SLC20A3 protein thus serves as a valuable tool in bridging the gap between basic research and clinical applications, paving the way for innovative strategies to address disorders associated with phosphate metabolism.
