Analytical Data
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基因名
KIAA0494
- Application
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别名
EF hand domain containing protein KIAA0494; EF-hand domain-containing protein KIAA0494; K0494_HUMAN; Kiaa0494
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75071
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表达区间
1-483aa
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分子量
80.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA0494, also known as the lysophosphatidic acid receptor 3 (LPA3), is a member of the KIAA gene family, which is implicated in various cellular processes such as proliferation, differentiation, and migration. The interest in KIAA0494 arises from its potential role in physiological and pathological conditions, including cancer and neurological disorders. Emerging studies indicate that KIAA0494 is involved in critical signaling pathways that mediate cell responses to extracellular signals, particularly related to the lysophospholipid signaling cascade. This cascade has been associated with several cancer types, making KIAA0494 a potential target for therapeutic intervention. Additionally, research has highlighted its functionality in regulating inflammatory responses and neuronal activity, pointing towards its importance in both the immune system and the nervous system. Despite this, the specific mechanisms and interactions of KIAA0494 remain largely unexplored, warranting further investigation to elucidate its role in disease states and to assess its therapeutic potential. The recombination and expression of KIAA0494 in heterologous systems could provide valuable insights into its biochemical properties, receptor interactions, and downstream signaling pathways, thereby laying the groundwork for future studies aimed at targeting KIAA0494 in clinical applications. Overall, the characterization of KIAA0494 and its recombinant protein holds significant promise for advancing our understanding of its biological functions and therapeutic implications in various disorders.












