Analytical Data
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基因名
AGR3
- Application
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别名
rMuAgr3, His; Agr3; Anterior gradient protein 3
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种属
Mouse
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8R3W7
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表达区间
I21-L165
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蛋白长度
Full Length of Mature Protein
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分子量
16-18 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AGR3 (anterior gradient 3) is a protein that has gained attention in cancer research due to its association with tumor progression and metastasis, particularly in breast cancer. Initially identified as a candidate gene involved in the development of the anterior portion of the embryo, AGR3 has since been implicated in various cellular processes, including cell proliferation, differentiation, and response to stress. Its expression is often upregulated in different cancer types, suggesting a role as a potential biomarker for malignancy. Research has focused on understanding the molecular mechanisms through which AGR3 influences cancer cell behavior, including its interactions with chaperone proteins and involvement in protein folding and stabilization. Moreover, AGR3 has been found to contribute to the epithelial-mesenchymal transition (EMT), a critical process for cancer cell migration and invasion. Given its roles in tumor biology, AGR3 is being investigated not only as a potential therapeutic target but also as a valuable marker for diagnosis and prognosis in oncology. Ongoing studies aim to elucidate the full spectrum of AGR3 functions and its interactions within the tumor microenvironment, providing insights that could lead to novel cancer treatments.
