Analytical Data
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Gene name
SIRPg
- Application
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Alternative Names
CD172g; CD172-G; SIRP-G; SIRP-B2; SIRPB2; SIRP-b2; SIRP-beta-2; SIRPgamma; CD172 antigen-like family member B; Signal-regulatory protein beta-2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9P1W8
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Expression Region
Glu29~Pro360
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Molecular Weight
41kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SIRPγ (Signal Regulatory Protein Gamma) is part of the SIRP family of proteins, which play crucial roles in regulating immune responses and cellular signaling. Research into SIRPγ has gained traction due to its significance in modulating the interactions between immune cells and their environment, particularly in relation to myeloid cells. Unlike other members of the SIRP family, SIRPγ has distinct structural and functional characteristics that suggest it might serve unique roles in both immune regulation and potential therapeutic applications. Studies have shown that SIRPγ influences the activation and proliferation of immune cells, and its dysregulation may be implicated in various pathological conditions, including autoimmune diseases and cancer. Because of its involvement in key signaling pathways, SIRPγ has emerged as a promising target in developing novel immunotherapies. The recombinant expression of SIRPγ protein provides a valuable tool for elucidating its functions, interactions, and mechanisms in immune response modulation. This research is essential for understanding how SIRPγ contributes to immune system homeostasis and for exploring its potential as a therapeutic target in treating immune-related disorders.
