Analytical Data
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基因名
DGCR6L
- Application
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别名
DiGeorge syndrome critical region 6-like protein
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BY27
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表达区间
1-220aa
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分子量
40.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DGCR6L, or DiGeorge Syndrome Critical Region Gene 6-Like, is a protein that plays a significant role in the developmental processes and cellular functions associated with the immune system and neural crest. Disruptions in the DGCR6L gene have been linked to the 22q11.2 deletion syndrome, commonly known as DiGeorge syndrome, which is characterized by a range of clinical manifestations, including immunodeficiency, congenital heart defects, and developmental delays. Given its critical involvement in embryonic development and immune regulation, researchers are increasingly focused on the characterization and functional analysis of recombinant DGCR6L protein. Studying this protein provides insight into its molecular mechanisms and interactions, paving the way for potential therapeutic approaches for conditions linked to its dysfunction. The recombination and expression of DGCR6L in various model systems are essential for elucidating its role in pathophysiology and for exploring its potential as a biomarker or therapeutic target. Understanding the structure-function relationship of DGCR6L could also contribute to the development of strategies aimed at mitigating the effects of genetic aberrations associated with DiGeorge syndrome and other related disorders. As research progresses, the recombinant DGCR6L protein may hold promise for advancing our understanding of genetic diseases and enhancing therapeutic options for affected individuals.
