Analytical Data
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基因名
CXXC4
- Application
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别名
Inhibition of the Dvl and axin complex protein
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H2H0
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表达区间
1-198aa
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分子量
48 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CXXC4, also known as Zinc finger protein 1 (ZFP1), plays a vital role in cellular processes including gene regulation, DNA damage response, and epigenetic modifications. Its distinctive CXXC domain allows for the binding of unmethylated CpG-rich DNA regions, making it a critical player in the maintenance of genomic integrity and regulation of gene expression. Research surrounding CXXC4 has intensified due to its implications in various diseases, particularly cancer, where dysregulation of its function can contribute to uncontrolled cell proliferation and tumorigenesis. The recombinant expression of CXXC4 protein aids in elucidating its biochemical properties, interaction networks, and functional roles in cellular pathways. Additionally, understanding the molecular mechanisms underlying CXXC4's function may provide insights into novel therapeutic strategies targeting its pathways. Studies have also explored its potential as a biomarker for certain cancers, emphasizing the need for further investigation into its role within the broader context of epigenetic regulation. Overall, the research into CXXC4 not only enhances our understanding of fundamental biological processes but also opens up possibilities for clinical applications in disease diagnosis and treatment.
