Analytical Data
-
Gene name
CXXC4
- Application
-
Alternative Names
Inhibition of the Dvl and axin complex protein
-
Species
Human
-
Source
E. coli
-
Tag
N- GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9H2H0
-
Expression Region
1-198aa
-
Molecular Weight
48 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CXXC4, also known as Zinc finger protein 1 (ZFP1), plays a vital role in cellular processes including gene regulation, DNA damage response, and epigenetic modifications. Its distinctive CXXC domain allows for the binding of unmethylated CpG-rich DNA regions, making it a critical player in the maintenance of genomic integrity and regulation of gene expression. Research surrounding CXXC4 has intensified due to its implications in various diseases, particularly cancer, where dysregulation of its function can contribute to uncontrolled cell proliferation and tumorigenesis. The recombinant expression of CXXC4 protein aids in elucidating its biochemical properties, interaction networks, and functional roles in cellular pathways. Additionally, understanding the molecular mechanisms underlying CXXC4's function may provide insights into novel therapeutic strategies targeting its pathways. Studies have also explored its potential as a biomarker for certain cancers, emphasizing the need for further investigation into its role within the broader context of epigenetic regulation. Overall, the research into CXXC4 not only enhances our understanding of fundamental biological processes but also opens up possibilities for clinical applications in disease diagnosis and treatment.
