Analytical Data
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基因名
TIMM21
- Application
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别名
TIM21-like protein, mitochondrial
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BVV7
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表达区间
1-248aa
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分子量
55.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TIMM21 is an important protein involved in the mitochondrial protein import machinery. It is part of the translocase of the inner mitochondrial membrane (TIM) complex, which facilitates the transfer of nuclear-encoded proteins into the mitochondria, where they undergo maturation and are integrated into various mitochondrial processes. The study of TIMM21 and its recombinant form has gained significant attention due to its potential implications in understanding mitochondrial diseases, metabolic disorders, and aging. Mitochondria are crucial for energy production, apoptosis, and cellular signaling, and disruptions in their function can lead to severe pathologies. Recombinant TIMM21 can be utilized to investigate its structure-function relationship, interaction with other mitochondrial proteins, and its role in the import process. Additionally, understanding the dynamics of TIMM21 can shed light on broader mitochondrial import mechanisms and their regulation. Research on TIMM21 not only provides insights into fundamental biological processes but also has the potential to inform therapeutic strategies for diseases linked to mitochondrial dysfunction, making it a valuable focus of molecular and cell biology studies.
