Analytical Data
-
基因名
CNOT8
- Application
-
别名
CAF1-like protein
-
种属
Human
-
表达系统
E. coli
-
标签
N- GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UFF9
-
表达区间
1-292aa
-
分子量
60.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CNOT8, a member of the CCR4-NOT complex, plays a critical role in RNA degradation and post-transcriptional regulation of gene expression. This protein is involved in various cellular processes, including mRNA stability, translation control, and cellular signaling pathways, making it a significant focus of research in molecular biology. Studies have shown that CNOT8 can interact with multiple RNA-binding proteins and is essential for maintaining cellular homeostasis. Abnormalities in CNOT8 expression and function have been implicated in several diseases, including cancer and neurological disorders, highlighting its potential as a therapeutic target. Consequently, understanding the structure and function of recombinant CNOT8 is crucial for elucidating its biological roles and the mechanisms underlying its involvement in pathophysiological conditions. Researchers are actively investigating recombinant CNOT8 to explore its interactions, functional domains, and impact on gene regulation, aiming to provide insights into the development of novel therapeutic strategies.
