Analytical Data
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基因名
SLC7A11
- Application
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别名
Amino acid transport system xc- (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UPY5
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表达区间
1-501aa
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分子量
58.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Translocator protein (TSPO), also known as 18 kDa mitochondrial protein or benzodiazepine receptor, has garnered significant attention in recent years due to its crucial role in various physiological and pathological processes. TSPO is predominantly located on the outer mitochondrial membrane and is involved in steroidogenesis, cell proliferation, and apoptosis. Its expression is upregulated in response to cellular stress, inflammation, and neurodegenerative disorders, making it a potential biomarker for various diseases, including Alzheimer's disease and cancer. The interest in TSPO has also led researchers to explore its potential as a therapeutic target. The study of TSPO and its recombinant protein forms has significant implications in drug development and understanding disease mechanisms. By generating and characterizing recombinant TSPO proteins, scientists aim to elucidate the functional roles of this protein in mammalian systems, explore its interaction with ligands, and assess its potential as a target for drug development. Furthermore, TSPO's unique characteristics and involvement in mitochondrial function make it a valuable candidate for studying metabolic disorders and neurobiology. Overall, the investigation of TSPO and its recombinant proteins is essential for advancing our knowledge in biomedical research and for the development of novel therapeutic strategies.
