Analytical Data
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基因名
HEPACAM2
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简介
The HEPACAM2 gene encodes a protein associated with an immunoglobulin superfamily that plays a role in mitosis. Knocking down this gene can lead to prophase cell arrest, abnormal nuclear morphology and apoptosis. HEPACAM2 can be used as a biomarker for the prognosis of colorectal adenocarcinoma. HEPACAM2 Protein, Rat (HEK293, His) is the recombinant rat-derived HEPACAM2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
HEPACAM family member 2; Mitotic kinetics regulator; MIKI
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种属
Rat
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
B5DEN8
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表达区间
L33-L350
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蛋白长度
Partial
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分子量
55-75 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HEPACAM2, also known as Hepatocellular carcinoma-associated protein 2, is a membrane protein that has garnered significant interest in cancer research, particularly in the study of hepatocellular carcinoma (HCC). This protein is implicated in cellular signaling pathways and has been shown to play a role in tumor progression and metastasis. As a member of the immunoglobulin superfamily, HEPACAM2 is expressed in various tissues, but its elevated levels in malignant tissues make it a potential biomarker for cancer diagnosis and prognosis. Recent studies have focused on characterizing the molecular mechanisms underlying HEPACAM2 function in cancer development, including its interaction with other proteins and its influence on the tumor microenvironment. Additionally, recombinant HEPACAM2 protein has been explored for its utility in therapeutic applications, such as vaccine development and targeted therapies. Understanding the precise role of HEPACAM2 in HCC and its potential as a therapeutic target offers promising avenues for improving cancer treatment outcomes, making it a focal point of ongoing research in oncology.
