Analytical Data
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Gene name
HEPACAM2
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简介
The HEPACAM2 gene encodes a protein associated with an immunoglobulin superfamily that plays a role in mitosis. Knocking down this gene can lead to prophase cell arrest, abnormal nuclear morphology and apoptosis. HEPACAM2 can be used as a biomarker for the prognosis of colorectal adenocarcinoma. HEPACAM2 Protein, Rat (HEK293, His) is the recombinant rat-derived HEPACAM2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
HEPACAM family member 2; Mitotic kinetics regulator; MIKI
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Species
Rat
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Source
HEK293
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Tag
C-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
B5DEN8
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Expression Region
L33-L350
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Protein Length
Partial
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Molecular Weight
55-75 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HEPACAM2, also known as Hepatocellular carcinoma-associated protein 2, is a membrane protein that has garnered significant interest in cancer research, particularly in the study of hepatocellular carcinoma (HCC). This protein is implicated in cellular signaling pathways and has been shown to play a role in tumor progression and metastasis. As a member of the immunoglobulin superfamily, HEPACAM2 is expressed in various tissues, but its elevated levels in malignant tissues make it a potential biomarker for cancer diagnosis and prognosis. Recent studies have focused on characterizing the molecular mechanisms underlying HEPACAM2 function in cancer development, including its interaction with other proteins and its influence on the tumor microenvironment. Additionally, recombinant HEPACAM2 protein has been explored for its utility in therapeutic applications, such as vaccine development and targeted therapies. Understanding the precise role of HEPACAM2 in HCC and its potential as a therapeutic target offers promising avenues for improving cancer treatment outcomes, making it a focal point of ongoing research in oncology.
