Analytical Data
-
基因名
GPA33
- Application
-
别名
Cell surface A33 antigen
-
种属
Rat
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 95% as determined by SDS-PAGE.
-
蛋白编号
D3ZRJ6
-
表达区间
Ile22~Ile235
-
分子量
30kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPA33, a cell surface glycoprotein, has garnered significant interest in cancer research due to its potential role as a biomarker and therapeutic target, particularly in colorectal cancer. Expressed predominantly in malignant tissues, GPA33 is involved in tumor cell proliferation and metastasis, making it a candidate for innovative cancer treatments. The rationale behind studying GPA33 lies in its restricted expression profile; it is largely absent in normal tissues, which underscores its specificity for cancer cells and minimizes potential off-target effects in therapeutic applications. Recent studies have shown that GPA33 can be targeted using monoclonal antibodies, resulting in enhanced anti-tumor activity and reduced tumor growth in preclinical models. Furthermore, the recombinant expression of GPA33 has opened avenues for developing targeted therapies and advanced drug delivery systems that exploit its characteristics. As researchers delve deeper into the functional mechanisms of GPA33, a clearer understanding of its role in cancer biology could pave the way for novel diagnostic tools and treatment strategies, aiming to improve patient outcomes in oncology. The investigation of GPA33 not only enriches our knowledge of tumor biology but also represents a promising frontier in precision medicine, emphasizing the need for continued exploration and innovation in this area.












