Analytical Data
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Gene name
CHUK
- Application
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Alternative Names
IKKA; TCF16
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Species
Human
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Source
Baculovirus
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Tag
His;GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15111
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Expression Region
E2-E745
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CHUK, also known as IKK-alpha, is a critical component of the inhibitor of kappa B kinase (IKK) complex, which plays a pivotal role in the regulation of the NF-kB signaling pathway. This pathway is essential for various cellular processes, including immune responses, inflammation, and cell survival. Dysregulation of NF-kB signaling has been implicated in numerous diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. Therefore, CHUK and its associated pathways have garnered significant attention in biomedical research. The reconstitution and characterization of CHUK recombinant proteins allow for in-depth studies of its biochemical properties and functional dynamics. By expressing CHUK in heterologous systems, researchers can elucidate its role in the NF-kB signaling cascade and explore its interactions with other proteins and cellular mechanisms. Such studies have the potential to uncover novel therapeutic targets and strategies for diseases where NF-kB is dysregulated. Consequently, the research on CHUK recombinant proteins is not only fundamental for understanding cell signaling but also provides insights into the development of innovative treatments for complex diseases.
