Recombinant Human; Cynomolgus RIIB/ACVR2B Protein (HEK293)，hFc

RIIB/ACVR2B

ACVR2B is a transmembrane kinase that forms the activin receptor complex and is essential for transducing activin signals. It regulates diverse processes including neuronal differentiation, hair follicle development, FSH production, wound healing, matrix production, immunosuppression, and carcinogenesis. RIIB/ACVR2B Protein, Human/Cynomolgus (HEK293, Fc) is the recombinant human/cynomolgus-derived RIIB/ACVR2B protein, expressed by HEK293, with C-hFc labeled tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Activin receptor type-2B; Activin receptor type IIB; ACTR-IIB; Acvr2b; ACTR-IIB

Human; Cynomolgus

HEK293

C-hFc

Greater than 90% as determined by SDS-PAGE.

Q13705 (S19-T137)

S40-T158

55-70 kDa, based on Bis-Tris PAGE under reducing conditions,.

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.