Analytical Data
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Gene name
BD-4
- Application
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Alternative Names
rRtBD-4; DEFB-4; Beta-defensin 104; DEFB4; DEFB104
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Species
Rat
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
O88514
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Expression Region
Q23-K63
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Protein Length
Full Length of Mature Protein
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Molecular Weight
10.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BD-4, a member of the human beta-defensin family, is a cationic antimicrobial peptide known for its role in innate immunity and antimicrobial defense. Research into BD-4 has surged due to its potential therapeutic implications, particularly in combatting antibiotic-resistant pathogens and modulating immune responses. This peptide exhibits broad-spectrum activity against various bacteria, fungi, and viruses, making it a valuable candidate in the field of infectious diseases. Additionally, BD-4 has been implicated in the regulation of inflammation and immune cell recruitment, contributing to the understanding of its dual role in host defense and immune modulation. The investigation of BD-4 as a recombinant protein offers promising avenues for developing novel antimicrobial therapies, as well as enhancing our knowledge of the molecular mechanisms underlying its action. Recent studies have focused on optimizing production methods for BD-4, characterizing its biochemical properties, and evaluating its efficacy in different biomedical applications. As the prevalence of multidrug-resistant infections continues to rise, BD-4 represents a compelling target for the development of next-generation antibiotics and immunotherapeutic strategies aimed at bolstering the body's natural defenses.
