Analytical Data
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基因名
RBP3
- Application
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别名
Interphotoreceptor retinoid-binding protein ;IRBPInterstitial retinol-binding protein;Protein 7S
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种属
Bovine
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12661
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表达区间
633-1231aa
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分子量
66.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RBP3, also known as Retinal Binding Protein 3, is a crucial protein involved in the transport of retinoids, specifically retinol (vitamin A), within the retina. It plays a significant role in the visual cycle by facilitating the delivery of retinol to the retinal pigment epithelium and photoreceptor cells, which are essential for maintaining phototransduction and overall visual function. Mutations in the RBP3 gene have been associated with various retinal diseases, including retinitis pigmentosa and age-related macular degeneration, making it an important target for research. The recombinant expression of RBP3 allows for the study of its structural and functional properties, which can provide insights into its role in retinal health and disease. Additionally, characterizing the protein through recombinant techniques can aid in the development of potential therapeutic strategies aimed at addressing retinal degenerative conditions. Understanding the mechanisms underlying RBP3's function and interactions within the visual system could open avenues for innovative treatments and pave the way for gene therapy approaches targeting retinal disorders linked to RBP3 dysfunction. As such, the study of RBP3 recombinant protein is not only relevant for basic biological research but also holds promise for translational applications in ophthalmology and vision science.
