Analytical Data
-
基因名
CAMKI gamma/CAMK1G
-
简介
The CAMK1G protein is a calcium/calmodulin-dependent protein kinase and a key component of the proposed calcium-triggered signaling cascade. This kinase exhibits the ability to phosphorylate the transcription factor CREB1 in vitro, suggesting its involvement in regulating cellular processes related to gene expression and transcriptional control. CAMKI gamma/CAMK1G Protein, Human (sf9, His, GST) is the recombinant human-derived CAMKI gamma/CAMK1G protein, expressed by Sf9 insect cells , with His, GST labeled tag.
- Application
-
别名
Calcium/calmodulin-dependent protein kinase type 1G; CaMKI gamma; CLICK III; CLICK3; VWS1
-
种属
Human
-
表达系统
Baculovirus
-
标签
His;GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96NX5-1
-
表达区间
M1-M476
-
蛋白长度
Full Length of Isoform-1
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CAMK1G, or Calcium/Calmodulin-dependent protein kinase I gamma, is a critical serine/threonine kinase that plays a significant role in various cellular processes, including calcium signaling, cell cycle regulation, and neuronal functions. As a member of the calcium/calmodulin-dependent protein kinase (CaMK) family, CAMK1G is activated upon binding to calcium-bound calmodulin, leading to phosphorylation of target proteins that modulate signal transduction pathways. Research has indicated its involvement in neuronal differentiation and synaptic plasticity, making it a potential candidate for studying neurological disorders. The interest in recombinant CAMK1G protein has surged, driven by the need to understand its precise molecular mechanisms and functional roles in health and disease. By producing this kinase in a recombinant form, researchers can investigate its enzymatic activities, interaction with substrates, and effects on signaling pathways in more controlled settings. This approach could aid in elucidating CAMK1G's contribution to various pathophysiological conditions, including neurodegenerative diseases and cancer, where altered calcium signaling and kinase activity are often implicated. The generation of recombinant CAMK1G protein not only facilitates functional assays and structural studies but also enhances the potential for therapeutic interventions targeting this kinase pathway. Overall, the study of CAMK1G and its recombinant protein offers promising avenues for advancing our understanding of cellular signaling networks and developing novel therapeutic strategies.
