Analytical Data
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基因名
SLC30A10
- Application
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别名
(ZnT-10)(Manganese transporter SLC30A10)(Solute carrier family 30 member 10)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6XR72
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表达区间
300-485aa
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分子量
27.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC30A10, a member of the solute carrier family, encodes a zinc transporter that plays a critical role in cellular zinc homeostasis. Mutations in this gene have been linked to various neurological and metabolic disorders, including hypozincemia and neurodegeneration, highlighting its importance in maintaining zinc levels within cells. Given the essential role of zinc in numerous biological processes such as enzyme function, DNA synthesis, and cell signaling, understanding the function of SLC30A10 is vital for elucidating the pathophysiological mechanisms of diseases associated with zinc imbalance. Research into the recombinant protein of SLC30A10 aims to unlock insights into its structure, function, and interaction with other cellular components, providing a potential avenue for therapeutic intervention. By analyzing this protein through techniques like crystallography and functional assays, scientists hope to design strategies to correct zinc transport deficiencies and mitigate disease symptoms, thus emphasizing the significance of SLC30A10 in both fundamental biology and clinical applications.
