Analytical Data
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Gene name
Artemin
- Application
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Alternative Names
NBN; EVN; ENOVIN; Neublastin; Neurotrophic Factor
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 97% as determined by SDS-PAGE.
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Uniprot
Q6AYE8
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Expression Region
Ala112~Gly224
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Protein Length
Partial
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Molecular Weight
18kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Artemin, a member of the glial cell line-derived neurotrophic factor (GDNF) family, plays a crucial role in the development and maintenance of the peripheral nervous system, particularly in promoting the survival and differentiation of dopaminergic neurons. First identified for its neuroprotective properties, Artemin has garnered significant interest due to its potential therapeutic applications in neurodegenerative diseases, such as Parkinson's disease, where dopaminergic neuron loss is a hallmark. The recombination of Artemin proteins in research settings allows for a deeper understanding of its biological functions and mechanisms, particularly in cellular signaling pathways. Furthermore, recombinant Artemin can be utilized in preclinical studies to assess its role in neuronal regeneration and repair, making it a candidate for developing novel treatment strategies for nerve injuries and neurodegenerative disorders. Recent advancements in biotechnological methods for producing high yields of functional recombinant proteins have enhanced research capabilities, facilitating the exploration of Artemin's effects on neuronal health and its potential for therapeutic interventions in disorders characterized by neuronal stress or degeneration. Through elucidating the mechanisms underpinning Artemin's actions, researchers aim to pave the way for innovative approaches to neuroprotection and regeneration in the nervous system.
