Analytical Data
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Gene name
BAFFR/TNFRSF13C
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简介
BAFFR/TNFRSF13C Protein, a B-cell receptor, specifically recognizes TNFSF13B/TALL1/BAFF/BLyS, playing a crucial role in promoting the survival of mature B-cells and enhancing the B-cell response, contributing to a healthy immune system. BAFFR/TNFRSF13C Protein, Human (HEK293, His, Fc) is the recombinant human-derived BAFFR/TNFRSF13C protein, expressed by HEK293, with C-His and N-hFc labeled tag.
- Application
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Alternative Names
rHuBAFF-R; CD268; TNFRSF13C; BR3
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Species
Human
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Source
HEK293
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Tag
C-His;N-hFc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96RJ3-1
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Expression Region
R6-A71
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Protein Length
Partial
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Molecular Weight
49.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BAFFR, also known as TNFRSF13C, is a receptor that plays a crucial role in the regulation of B cell survival and differentiation. It interacts with B cell activating factor (BAFF), which is essential for the maintenance of B cell populations in the peripheral immune system. Recent studies have highlighted the significance of BAFFR in various autoimmune diseases, where dysregulation of BAFF and its receptors can lead to the proliferation of autoreactive B cells. Furthermore, BAFFR has emerged as a potential target for therapeutic interventions to control autoimmune conditions and B cell malignancies. Research on recombinant BAFFR protein involves examining its structure, function, and interaction with ligands, which can provide insights into the mechanisms of B cell-mediated immunity. Understanding these interactions at a molecular level is critical for developing novel therapies aimed at modulating immune responses, especially in diseases characterized by B cell dysregulation. This recombinant protein research not only contributes to fundamental immunology but also holds promise for clinical applications in treating autoimmune disorders and enhancing vaccine responses.
