Analytical Data
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Gene name
glycoprotein D/gD
- Application
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Alternative Names
Envelope glycoprotein D; Gd; US6
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Species
Virus
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P03172
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Expression Region
K26-T310
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Protein Length
Partial
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Molecular Weight
42.79 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Glycoprotein D (gD) is a critical viral envelope glycoprotein found in the herpes simplex virus (HSV), particularly in HSV-1 and HSV-2. Studies have shown that gD plays a vital role in the virus's ability to enter host cells by mediating the initial attachment and fusion processes. As a key target for antiviral strategies and vaccine development, gD has garnered significant research interest. Its immunogenic properties make it an attractive candidate for eliciting an immune response in vaccination efforts, potentially providing protection against HSV infection. Additionally, gD is involved in inducing neutralizing antibodies, making it essential for understanding host-pathogen interactions. The recombinant production of gD allows for detailed studies on its structure-function relationships and its role in viral pathogenesis. Researchers utilize various expression systems to produce gD in sufficient quantities for further analysis, including its application in immunological assays and the development of therapeutic vaccines. Overall, the investigation of glycoprotein D not only enhances our understanding of HSV biology but also contributes to the ongoing efforts to combat herpesvirus infections through innovative therapeutic and preventive measures.
