Analytical Data
-
Gene name
PPM1F
- Application
-
Alternative Names
KIAA0015; POPX2; CaMKPase
-
Species
Human
-
Source
E. coli
-
Tag
GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P49593-1
-
Expression Region
M1-S454
-
Protein Length
Full Length of Isoform-1
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPM1F, also known as Protein Phosphatase Magnesium/Manganese Dependent 1F, is a member of the protein phosphatase family, which plays a crucial role in various cellular processes by regulating protein phosphorylation. Dysregulation of PPM1F has been linked to several diseases, including cancer, metabolic disorders, and neurodegenerative diseases. This protein is known to dephosphorylate specific target proteins involved in signaling pathways, thereby influencing cellular functions such as cell cycle progression, apoptosis, and stress responses. Given its pivotal role in these biological processes, PPM1F has garnered significant attention in research aimed at understanding its molecular mechanisms and potential as a therapeutic target. Researchers are particularly interested in the development of recombinant PPM1F proteins to study its structure-function relationship and to identify potential inhibitors or modulators. Advances in recombinant DNA technology have enabled the production of PPM1F in various expression systems, facilitating biochemical assays and structural analyses. By investigating the functional dynamics of PPM1F, scientists hope to uncover insights into its role in health and disease, paving the way for novel therapeutic strategies that could mitigate the impact of diseases related to phosphatase dysregulation.
