Analytical Data
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基因名
PPM1F
- Application
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别名
KIAA0015; POPX2; CaMKPase
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种属
Human
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表达系统
E. coli
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标签
GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49593-1
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表达区间
M1-S454
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蛋白长度
Full Length of Isoform-1
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PPM1F, also known as Protein Phosphatase Magnesium/Manganese Dependent 1F, is a member of the protein phosphatase family, which plays a crucial role in various cellular processes by regulating protein phosphorylation. Dysregulation of PPM1F has been linked to several diseases, including cancer, metabolic disorders, and neurodegenerative diseases. This protein is known to dephosphorylate specific target proteins involved in signaling pathways, thereby influencing cellular functions such as cell cycle progression, apoptosis, and stress responses. Given its pivotal role in these biological processes, PPM1F has garnered significant attention in research aimed at understanding its molecular mechanisms and potential as a therapeutic target. Researchers are particularly interested in the development of recombinant PPM1F proteins to study its structure-function relationship and to identify potential inhibitors or modulators. Advances in recombinant DNA technology have enabled the production of PPM1F in various expression systems, facilitating biochemical assays and structural analyses. By investigating the functional dynamics of PPM1F, scientists hope to uncover insights into its role in health and disease, paving the way for novel therapeutic strategies that could mitigate the impact of diseases related to phosphatase dysregulation.












