Analytical Data
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Gene name
Cope1
- Application
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Alternative Names
Cope; Coatomer subunit epsilon
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Species
Mouse
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Source
Baculovirus
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Tag
Strep;His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O89079
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Expression Region
M1-A308
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Cope1 is a member of the C3HC4 RING-finger E3 ubiquitin ligase family, playing a crucial role in the ubiquitin-proteasome system, which regulates protein degradation and turnover. Research on Cope1 has gained momentum due to its involvement in various cellular processes, including cell cycle regulation, apoptosis, and stress responses. Dysregulation of Cope1 has been implicated in several pathological conditions, such as cancer, neurodegenerative diseases, and inflammation. Understanding the structure and function of Cope1, particularly through the study of its recombinant protein, has the potential to elucidate its interacting partners and downstream signaling pathways. This knowledge could aid in the development of therapeutic strategies targeting the ubiquitin-proteasome system to treat diseases associated with Cope1 dysfunction. Additionally, the production of Cope1 recombinant protein allows for detailed biochemical assays, structural analyses, and the exploration of its enzymatic activity, thereby contributing to a more comprehensive understanding of its functional roles within the cell. The ongoing studies on Cope1 are expected to reveal valuable insights into its biological significance and therapeutic potential, making it a focus of interest in molecular biology and medical research.
