Analytical Data
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Gene name
FABP7
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简介
FABP7 Protein, Human (His) expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms[1].
- Application
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Alternative Names
rHuFABP7, His; Fatty Acid-Binding Protein Brain; B-FABP; Brain-Type Fatty Acid-Binding Protein
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Species
Human
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15540-1
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Expression Region
V2-A132
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Protein Length
Full Length of Isoform-1
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Molecular Weight
16.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fatty acid-binding protein 7 (FABP7), also known as brain FABP, is primarily expressed in the brain and plays a crucial role in the transport of fatty acids and influence on neurodevelopment. Its involvement in various physiological and pathological processes has garnered significant interest in recent years. Research has demonstrated that FABP7 is essential for neuronal differentiation, regulation of lipid metabolism, and maintenance of brain homeostasis. Notably, aberrations in FABP7 expression have been linked to neurodevelopmental disorders, including schizophrenia and autism spectrum disorders, highlighting its potential as a biomarker for these conditions. Moreover, FABP7 has been implicated in neuroinflammation and neurodegeneration, suggesting that it may serve as a therapeutic target in diseases such as Alzheimer's. The development of recombinant FABP7 proteins has facilitated in-depth studies of its structure-function relationships and interactions with fatty acids, paving the way for novel lipid-based therapies and interventions in neurodegenerative disorders. Understanding the biochemical pathways influenced by FABP7 could lead to innovative strategies for modulating its activity and addressing related neurological diseases. As the field continues to evolve, further exploration of FABP7’s role in brain function and pathology remains a promising avenue for research, with implications for both basic science and clinical applications.
