Analytical Data
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基因名
NRBF2
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简介
NRBF2 protein may regulate transcriptional activation through target nuclear receptors and act as a transcriptional activator in vitro. It participates in starvation-induced autophagy, binding to PI3K complex I (PI3KC3-C1) and stabilizing its assembly. NRBF2 Protein, Human (sf9, His-GST) is the recombinant human-derived NRBF2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
- Application
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别名
Nuclear receptor-binding factor 2; Comodulator of PPAR and RXR; COPR
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种属
Human
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表达系统
Baculovirus
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标签
N-His;N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96F24-1
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表达区间
M1-N287
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蛋白长度
Full Length of Isoform-1
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分子量
61 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NRBF2, or Nutrient-Regulated Gene Product 2, is a crucial protein implicated in various cellular processes, including nutrient sensing and metabolic regulation. Research into NRBF2 has gained significance due to its potential role in understanding metabolic disorders and diseases such as obesity and diabetes. This protein is known to interact with key signaling pathways that mediate nutrient availability and cellular response, making it a vital focal point for studying how cells adapt to fluctuating nutrient environments. Recent studies have indicated that NRBF2 may influence the activity of essential metabolic enzymes and transcription factors, thereby regulating gene expression related to energy homeostasis. Furthermore, its involvement in cellular stress responses and potential implications in cancer progression have sparked interest in exploring NRBF2 as a therapeutic target. As scientists continue to investigate NRBF2's structure, functions, and interactions, the hope is to elucidate its precise mechanisms and contributions to health and disease, paving the way for novel strategies in metabolic health management and cancer treatment. Understanding NRBF2's role offers a promising avenue for developing interventions that could modulate its activity, providing insights into how we can better manage conditions associated with metabolic dysregulation.
