Analytical Data
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基因名
ZMYND19
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简介
ZMYND19 Protein, implicated in GPR24/MCH-R1 signaling, suggests a role in modulating the associated pathways. Its interaction with GPR24/MCH-R1 indicates regulatory involvement. Mechanisms and downstream effects of ZMYND19 in GPR24/MCH-R1 signaling require further elucidation. Exploring ZMYND19's functions may provide insights into its role in cellular responses, offering potential interventions in G protein-coupled receptor pathways. ZMYND19 Protein, Human (His) is the recombinant human-derived ZMYND19 protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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别名
Zinc Finger MYND Domain-Containing Protein 19; Melanin-Concentrating Hormone Receptor 1-Interacting Zinc Finger Protein; MCH-R1-Interacting Zinc Finger Protein; ZMYND19; MIZIP
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96E35
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表达区间
M1-R227
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氨基酸序列
MTDFKLGIVRLGRVAGKTKYTLIDEQDIPLVESYSFEARMEVDADGNGAKIFAYAFDKNRGRGSGRLLHELLWERHRGGVAPGFQVVHLNAVTVDNRLDNLQLVPWGWRPKAEETSSKQREQSLYWLAIQQLPTDPIEEQFPVLNVTRYYNANGDVVEEEENSCTYYECHYPPCTVIEKQLREFNICGRCQVARYCGSQCQQKDWPAHKKHCRERKRPFQHELEPER
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蛋白长度
Full Length
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZMYND19 is a member of the ZMYND family of proteins, which are known to play critical roles in cellular processes such as transcriptional regulation, chromatin remodeling, and DNA damage response. Research into ZMYND19 has gained momentum due to its implications in various biological functions and potential links to diseases, particularly cancer. The protein is characterized by the presence of several functional domains, including a ZMYND domain that interacts with histones, suggesting its involvement in epigenetic regulation. Recent studies have highlighted ZMYND19’s role in modulating the transcription of target genes through its interaction with nucleosomes, affecting gene expression and cellular differentiation. Furthermore, alterations in ZMYND19 expression or function have been associated with the pathogenesis of certain malignancies, marking it as a potential biomarker or therapeutic target. Investigating ZMYND19 and its recombinant forms can provide valuable insights into not only its biological functions but also its mechanisms in disease contexts, paving the way for novel therapeutic strategies. The development of recombinant ZMYND19 protein will enable detailed functional studies, structural analyses, and screening assays to unravel its roles in transcriptional regulation and broader cellular processes, contributing to our understanding of gene expression modulation and cancer biology.
