Analytical Data
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基因名
KLRB1F/CD161f
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简介
The KLRB1F/CD161f protein is thought to bind CLEC2I/Clr-g, activate natural killer cells and provide costimulation for IL-2 production and T cell proliferation. This dual function highlights its critical role in coordinating immune responses. KLRB1F/CD161f Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived KLRB1F/CD161f protein, expressed by HEK293 , with N-hFc labeled tag.
- Application
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别名
Killer cell lectin-like receptor subfamily B member 1F; CD161f; Nkrp1f
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种属
Mouse
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表达系统
HEK293
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标签
N-hFc
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8VD98
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表达区间
Q67-V217
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蛋白长度
Extracellular Domain
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分子量
50-55 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLRB1F/CD161f is a novel receptor belonging to the KLRB (Killer Cell Lectin-like Receptor B) family, playing a significant role in the immune response, particularly in natural killer (NK) cells and T cell activation. The research background for KLRB1F/CD161f focuses on its potential implications in immune regulation and its involvement in various diseases, including cancer and viral infections. Previous studies have highlighted the importance of KLRB family members in identifying and modulating immune cell interactions, making KLRB1F/CD161f an interesting target for therapeutic interventions. Understanding the structure, function, and signaling pathways associated with this receptor can reveal insights into immune mechanisms and aid in the development of novel immunotherapies. Investigating its ligand specificity and downstream effects on immune cell function could enhance our understanding of NK and T cell biology, ultimately contributing to more effective treatment strategies for immune-related conditions. This makes KLRB1F/CD161f a promising subject of research in the field of immunology and cancer therapy, with the potential to uncover new pathways for enhancing immune responses against tumors and pathogens.
