Analytical Data
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基因名
WIBG
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简介
WIBG is a central regulator of the exon junction complex (EJC) and serves as a critical EJC disassembly factor in post-transcriptional processes. WIBG is located upstream of exon-exon junctions on mRNA and destroys mature EJCs on spliced mRNAs during translation, thereby promoting the removal and recycling of EJCs. WIBG Protein, Human (His) is the recombinant human-derived WIBG protein, expressed by E. coli , with C-6*His labeled tag.
- Application
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别名
Partner of Y14 and Mago; Protein Wibg Homolog; WIBG; PYM
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种属
Human
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表达系统
E. coli
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BRP8
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表达区间
M1-L204
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氨基酸序列
MEAAGSPAATETGKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPELPPGLSPEATAPVTPSRPEGGEPGLSKTAKRNLKRKEKRRQQQEKGEAEALSRTLDKVSLEETAQLPSAPQGSRAAPTAASDQPDSAATTEKAKKIKNLKKKLRQVEELQQRIQAGEVSQPSKEQLEKLARRRALEEELEDLELGL
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蛋白长度
Full Length
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分子量
30 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WIBG, or Wilms' tumor 1-interacting protein, is a crucial molecule implicated in various cellular processes, including gene regulation, apoptosis, and stress response. Its role in tumorigenesis, particularly in cancers such as Wilms' tumor, has garnered significant attention from researchers. The study of WIBG recombinant proteins has become essential for understanding its structure-function relationships and the molecular mechanisms underlying its interactions with other cellular proteins. Recombinant protein technology enables the production of purified WIBG, allowing for detailed biochemical characterization and functional assays. By elucidating the structure of WIBG and its binding partners, scientists aim to uncover potential pathways that could be targeted for therapeutic interventions. Furthermore, understanding WIBG's function may provide insights into its role in developmental processes and its contribution to cancer pathology, ultimately paving the way for novel diagnostic and treatment strategies. As the field of cancer research evolves, the investigation of WIBG and its associated pathways remains pivotal, emphasizing the importance of recombinant protein studies in advancing our knowledge of complex biological systems.
