Analytical Data
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Gene name
WBP2
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简介
WBP2 protein is not mentioned in the provided paragraph. If you have another paragraph or topic you'd like summarized with WBP2 as the subject, please provide it, and I'll be happy to assist. WBP2 Protein, Human (His) is the recombinant human-derived WBP2 protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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Alternative Names
WW Domain-Binding Protein 2; WBP-2; WBP2
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Species
Human
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q969T9-1
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Expression Region
M1-A100
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Protein Length
Partial
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Molecular Weight
14 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WBP2, or Wnt-binding protein 2, is a significant regulator in cellular signaling pathways, particularly in the context of the Wnt signaling cascade, which is crucial for various biological processes such as cell proliferation, differentiation, and apoptosis. Research into WBP2 has gained momentum due to its involvement in key cellular functions and its potential implications in disease mechanisms, particularly in cancer progression and metastasis. Studies indicate that WBP2 interacts with multiple proteins within the Wnt pathway, influencing β-catenin activity and thus affecting gene expression related to cell growth and development. Its role in oncogenesis has garnered interest, as aberrations in the Wnt signaling pathway are frequently linked to tumorigenesis. Understanding the molecular dynamics of WBP2 and its interactions can provide insights into therapeutic targets for cancer treatment and potentially other disorders associated with Wnt signaling dysregulation. Consequently, the recombinant expression of WBP2 protein for structural and functional studies is essential, paving the way for further investigations into its biological roles and therapeutic potential. This research aims to elucidate the mechanisms of WBP2 action and its significance within cellular contexts, enhancing our grasp of its contributions to health and disease.
