Analytical Data
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基因名
EPDR1
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简介
In the rat model, the EPDR1 protein plays a key regulator role by binding to and activating the TIE2 receptor, initiating its tyrosine phosphorylation. This interaction affects processes of endothelial development that are distinct from the effects of VEGF, which mediates interactions between the endothelium and the surrounding matrix and interstitium. EPDR1 Protein, Human (HEK293, His) is the recombinant human-derived EPDR1 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
Mammalian ependymin-related protein 1; EPDR1; Upregulated in colorectal cancer gene 1 protein; MERP1
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UM22-1
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表达区间
A38-S223
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氨基酸序列
APRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQPWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTINYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCS
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蛋白长度
Full Length of Isoform-1 Mature Protein
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分子量
28 kDa & 33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EPDR1, or epithelial-derived protein 1, is a protein of significant interest in the field of molecular biology due to its involvement in various cellular processes, including cell proliferation, adhesion, and differentiation. Research indicates that EPDR1 is expressed in epithelial tissues and may play a crucial role in maintaining epithelial integrity and function. Abnormal expression of EPDR1 has been linked to several pathological conditions, including cancer, where it might contribute to tumorigenesis and metastasis. Understanding the molecular mechanisms underlying EPDR1 function could provide valuable insights into the development of therapeutic strategies for diseases characterized by epithelial dysfunction. The recombinant expression of EPDR1 in various host systems allows for in-depth functional studies and the exploration of its potential as a biomarker or therapeutic target. By producing EPDR1 as a recombinant protein, researchers can investigate its structural properties, interactions with other proteins, and its role in signaling pathways relevant to cancer and other diseases. As such, the study of EPDR1 is not only pivotal for elucidating fundamental biological processes but also holds promise for advancing clinical applications in oncology and regenerative medicine.
