Analytical Data
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Gene name
ART4/CD297
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简介
ART4/CD297 Protein belongs to the Arg-specific ADP-ribosyltransferase family. ART4/CD297 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ART4/CD297 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1
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Species
Cynomolgus
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Source
HEK293
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Tag
C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
G7PJY0
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Expression Region
T31-K300
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AA Sequence
TAAPTVIRIWLLGGLLPFLLLLSGLQRPTDGSEVAMKIDFDFAPGSFDDQYQGCSKEVMEKLTQGDYFTKDIEAQKNYFGMWQKAHLTWLNQGKVLPQNMTTTHAVAILFYTLNSNVRSNFTRAVAYVARAPQQYERSFQFKYLHYYLTTAVQLLRKDSVMKNGTPLCYEVHYRTKDVHFSAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSLKKEVLIPPYELFKVINMSSHPRGNWLQLRSTGNLSTYNCQLLK
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Protein Length
Partial
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Molecular Weight
40-53 kDa.
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The ART4/CD297 protein, a member of the CD family of receptors, has garnered attention in recent years due to its pivotal role in immune system regulation and cell signaling. Emerging research indicates that ART4 functions as a nucleotide sugar transporter, participating in the biosynthesis of glycoproteins and glycolipids that are crucial for cellular communication and immune responses. Its expression is primarily observed in immune cells, such as lymphocytes, where it may influence T cell activity and differentiation. Abnormalities in ART4/CD297 expression have been linked to various immunological diseases, including autoimmune disorders and malignancies. For these reasons, understanding the structure and function of ART4/CD297 can provide valuable insights into its potential as a therapeutic target. Researchers are exploring the possibilities of using recombinant ART4/CD297 proteins to elucidate its signaling pathways, interactions with other cell surface receptors, and its overall impact on immune responses. Insights gained from these studies may pave the way for novel immunotherapeutic strategies, contributing to the development of treatments for disorders characterized by immune dysregulation.
