Analytical Data
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Gene name
CRY1
- Application
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Alternative Names
CRY1；PHLL1；Cryptochrome-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16526
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Expression Region
1-586aa
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AA Sequence
MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGIN RWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEY DSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTY KRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGF DTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTG LSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQE GWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWL SCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNA PEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLL ASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLL KQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN
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Molecular Weight
90 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CRY1, or Cryptochrome 1, is a pivotal protein involved in the regulation of circadian rhythms and various physiological processes in organisms ranging from plants to mammals. Originally identified as a photoreceptor that mediates the effects of light on biological clocks, CRY1 plays a crucial role in the synchronization of the circadian cycle with environmental light-dark cycles. Research has demonstrated that CRY1 not only influences circadian rhythms but also participates in the regulation of gene expression, cellular signaling pathways, and responses to environmental stress. The investigation of recombinant CRY1 proteins has gained significant attention in the fields of chronobiology and molecular biology, as these proteins are essential for elucidating the mechanistic insights of light perception and circadian regulation. Recombinant CRY1 proteins, produced through techniques such as recombinant DNA technology, allow scientists to study the protein's structure-function relationships and interactions with other molecular partners in vitro. Understanding CRY1's role in these processes is vital for uncovering the underlying mechanisms driving circadian biology, with implications for health, agriculture, and the development of therapeutics targeting circadian-related disorders. Overall, research on CRY1 recombinant proteins continues to provide essential insights into the complexity of circadian biology and its influence on various biological systems.
