Analytical Data
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基因名
TRAM1
- Application
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别名
TRAM1；TRAM；Translocating chain-associated membrane Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15629
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表达区间
1-374aa
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氨基酸序列
MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIF VTLQYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEY MLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPT ILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYI GLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGF SLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGT ENGVNGTLTSNVADSPRNKKEKSS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRAM1 (Translocating Chain-Associated Membrane Protein 1) is a crucial protein involved in the translocation process of polypeptides across the endoplasmic reticulum (ER) membrane, playing a vital role in protein synthesis and maturation. Research on TRAM1 has gained significance due to its implications in various biological processes and diseases, including cancer and neurodegenerative disorders. Studies have shown that TRAM1 functions in the recognition and integration of nascent polypeptides into the ER membrane, which is essential for proper protein folding and eventual trafficking to their functional destinations. The understanding of TRAM1's structure and function is critical for deciphering the mechanisms underlying protein translocation and for developing therapeutic strategies targeting related pathologies. Recent advances in recombinant protein technology have facilitated the study of TRAM1, allowing researchers to produce and characterize this protein in vitro. Investigating TRAM1 through recombinant methods not only enhances our comprehension of its biological roles but also provides insights into its potential as a drug target. Overall, TRAM1 stands at the intersection of molecular biology and therapeutic development, making it a focal point for ongoing research in the field of cellular biology.
