Analytical Data
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基因名
PFN3
- Application
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别名
PFN3；Profilin-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P60673
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表达区间
1-137aa
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氨基酸序列
MGDWKVYISA VLRDQRIDDV AIVGHADNSC VWASRPGGLL AAISPQEVGV LTGPDRHTFL QAGLSVGGRR CCVIRDHLLA EGDGVLDART KGLDARAVCV GRAPRALLVL MGRRGVHGGI LNKTVHELIR GLRMQGA
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PFN3 (Profilin 3) is a member of the profilin family of proteins, which play crucial roles in actin cytoskeleton dynamics and various cellular processes, including cell shape, motility, and signaling. Research into PFN3 has gained interest due to its potential implications in both normal cellular functions and pathological conditions. Unlike its well-studied counterparts, PFN1 and PFN2, the specific functions and mechanisms of PFN3 remain less understood. Preliminary studies suggest that PFN3 may be involved in neurodevelopment and may play a role in certain neurological disorders. Additionally, the expression levels of PFN3 have been correlated with various cancers, indicating its potential as a biomarker or therapeutic target. The recombinant protein of PFN3 provides an invaluable tool for investigating its biochemical properties, interactions with actin and other binding partners, and its role in cellular signaling pathways. Understanding PFN3's function could reveal new insights into cell behavior and highlight novel avenues for therapeutic intervention in diseases where actin dynamics are disrupted. Therefore, the study of recombinant PFN3 protein is essential for elucidating its biological roles and potential applications in medical research.
