Analytical Data
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基因名
UBXD5
- Application
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别名
UBX domain-containing Protein 11. Colorectal tumor-associated antigen COA-1. Socius. UBX domain-containing Protein 5
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T124
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表达区间
1-512 aa
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氨基酸序列
MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILGGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQRMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGSSPCPGPSPSPQ
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分子量
83.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UBXD5, also known as ubiquitin regulatory X domain-containing protein 5, plays a crucial role in cellular processes by regulating the ubiquitin-proteasome pathway, which is essential for protein degradation, quality control, and cellular signaling. This protein is particularly interesting due to its interaction with the proteasome and various ubiquitin-conjugating enzymes, which facilitates the recognition and ubiquitination of substrates destined for degradation. Recent research has highlighted its potential involvement in several diseases, including cancer and neurodegenerative disorders, as abnormalities in protein degradation mechanisms are often linked to tumorigenesis and the accumulation of misfolded proteins. Moreover, UBXD5 is implicated in regulating cellular responses to stress and maintaining proteostasis, further emphasizing its biological significance. Understanding the structural and functional characteristics of UBXD5 may provide insights into its mechanism of action and its role in health and disease. Consequently, the study of UBXD5 recombinant protein not only contributes to a deeper understanding of protein homeostasis but also holds promise for the development of novel therapeutic strategies targeting the ubiquitin-proteasome system. This makes UBXD5 an attractive target for further investigation in both basic research and pharmacological applications.
