Analytical Data
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基因名
KREMEN1
- Application
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别名
KREMEN1；KREMEN；KRM1；；Kremen Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96MU8-2
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表达区间
1-394aa
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氨基酸序列
MAPPAARLAL LSAAALTLAA RPAPSPGLGP GPECFTANGA DYRGTQNWTA LQGGKPCLFW NETFQHPYNT LKYPNGEGGL GEHNYCRNPD GDVSPWCYVA EHEDGVYWKY CEIPACQMPG NLGCYKDHGN PPPLTGTSKT SNKLTIQTCI SFCRSQRFKF AGMESGYACF CGNNPDYWKY GEAASTECNS VCFGDHTQPC GGDGRIILFD TLVGACGGNY SAMSSVVYSP DFPDTYATGR VCYWTIRVPG ASHIHFSFPL FDIRDSADMV ELLDGYTHRV LARFHGRSRP PLSFNVSLDF VILYFFSDRI NQAQGFAVLY QAVKEELPQE RPAVNQTVAE VITEQANLSV SAARSSKVLY VITTSPSHPP QTVPGSNSWA PPMGAGSHRV EGWT
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分子量
43 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KREMEN1, a member of the kringle domain-containing protein family, has garnered considerable attention in recent years due to its involvement in various biological processes, including cellular signaling and tissue development. This protein plays a crucial role in regulating the Wnt/β-catenin signaling pathway, which is essential for embryonic development and stem cell maintenance. Dysregulation of KREMEN1 has been implicated in several diseases, notably cancer and neurological disorders, making it a potential therapeutic target. Researchers have focused on the recombinant production of KREMEN1 to investigate its physiological functions and develop inhibitors or modulators for clinical applications. By leveraging advanced protein expression techniques, scientists aim to create a stable and functional form of KREMEN1 for biochemical assays, structural studies, and potential drug development. The elucidation of KREMEN1's structure-function relationships and its interaction with various signaling molecules holds promise for enhancing our understanding of its role in health and disease. Moreover, the investigation of KREMEN1 recombinant protein could pave the way for novel strategies in regenerative medicine and cancer therapy, highlighting its significance in both basic and applied research.
