Analytical Data
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Gene name
TTC9
- Application
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Alternative Names
TTC9; KIAA0227; TTC9A; Tetratricopeptide repeat Protein 9A; TPR repeat Protein 9A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92623
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Expression Region
1-222 aa
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AA Sequence
MERKGSAAGA KGNPSPPAAG EGQRPPPPLC VPGGGGGAPA RGQVGAAAEP AELIRRAHEF KSQGAQCYKD KKFREAIGKY HRALLELKGL LPPPGERERD SRPASPAGAL KPGRLSEEQS KTVEAIEIDC YNSLAACLLQ AELVNYERVK EYCLKVLKKE GENFKALYRS GVAFYHLGDY DKALYYLKEA RTQQPTDTNV IRYIQLTEMK LSRCSQREKE AM
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Molecular Weight
24.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TTC9, or Tetratricopeptide Repeat Protein 9, is a member of the TTC protein family, characterized by its distinctive tetratricopeptide repeat motifs that play crucial roles in protein-protein interactions. The importance of TTC9 has emerged from its potential involvement in various biological processes, including cellular signaling, stress responses, and the regulation of gene expression. Recent studies have highlighted its significance in several pathophysiological conditions, suggesting a role in neurodegenerative diseases, cancer, and developmental disorders. Research on recombinant TTC9 proteins has aimed to delineate their structural features and functional mechanisms, facilitating a deeper understanding of their biological significance. Techniques such as X-ray crystallography and nuclear magnetic resonance spectroscopy have been employed to elucidate the conformation and interaction properties of TTC9. Furthermore, the development of recombinant expression systems has enabled the generation of large quantities of purified TTC9 protein for functional assays, paving the way for targeted investigations into its role in cellular pathways. As scientists continue to explore the implications of TTC9 in health and disease, the study of its recombinant forms remains pivotal in uncovering novel therapeutic targets and advancing our understanding of complex biological mechanisms. This ongoing research not only aims to clarify the physiological functions of TTC9 but also holds promise for informing drug discovery and developing innovative treatments for related disorders.
